Last updated: May 2026
Summary: MOTS-c is a synthetic 16-amino-acid mitochondrial-derived peptide (MDP) encoded within the 12S rRNA region of the mitochondrial genome. PeptideDropship supplies research-grade MOTS-c to verified B2B partners under strict research-use-only labeling for mitochondrial biology, cellular energetics, and metabolic research applications. 99%+ purity verified by HPLC and mass spectrometry, third-party COAs per batch, no MOQ, US 24-hour fulfillment. For research use only — not for human consumption.
Technical specifications
| Parameter | Value |
|---|---|
| Peptide name | MOTS-c (Mitochondrial Open Reading Frame of 12S rRNA Type-C) |
| Type | Synthetic 16-amino-acid mitochondrial-derived peptide (MDP) |
| Sequence | Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg |
| Sequence (1-letter) | MRWQEMGYIFYPRKLR |
| Molecular formula | C₁₀₇H₁₆₇N₃₁O₂₂S₂ |
| Molecular weight | ~2174.5 g/mol |
| CAS number | 1627580-64-6 |
| Form | Lyophilized white powder |
| Standard pack sizes | 5 mg, 10 mg vials |
| Storage | −20°C lyophilized; 2–8°C after reconstitution |
Research context
MOTS-c was characterized in academic mitochondrial biology research in the early 2010s as one of several mitochondrial-derived peptides (MDPs) encoded within mitochondrial DNA rather than the nuclear genome. The research context is mitochondrial-encoded peptide biology, cellular energetics, and related metabolic pathway research. Research-grade MOTS-c supplied through PeptideDropship is for laboratory research applications only.
Manufacturing and quality control
MOTS-c is produced via solid-phase peptide synthesis (SPPS) and independently verified by a third-party laboratory before release. Standard QC includes mass spectrometry for molecular weight confirmation, reverse-phase HPLC for purity quantification (99%+ standard), counterion content documentation, Karl Fischer water content, and LAL endotoxin testing available on request. The full COA ships with every order.
Wholesale availability
- No minimum order quantity
- Tiered pricing — per-unit cost decreases with monthly volume
- 24-hour fulfillment from US-based warehouse
- API integration for automated order routing
White-label and private-label options
Generic, white-label, or private-label fulfillment available. See the white-label vs. private-label guide.
Packaging, shipping, and storage
MOTS-c ships as lyophilized powder in sealed amber vials with tamper-evident closure. Shock-protection packaging is standard. Cold-chain shipping is available. Lyophilized form is stable at room temperature for short-duration transit.
Compliance and labeling
MOTS-c is supplied to verified B2B partners exclusively for research use under strict research-use-only labeling. The compound has been subject to consumer-facing marketing in some jurisdictions; PeptideDropship does not endorse, support, or supply for any consumer-facing or therapeutic application. Resellers are responsible for maintaining strict research-use-only framing on all customer-facing materials, the FDA disclaimer, and compliance with applicable regulations.
FAQ
What’s distinctive about MOTS-c as a research peptide?
MOTS-c is one of several mitochondrial-derived peptides (MDPs) — peptides encoded within the mitochondrial DNA rather than the nuclear genome. This makes it a research subject in mitochondrial biology specifically. Other MDPs in the same family include the Humanin family of peptides.
What pack sizes are available?
Standard pack sizes are 5 mg and 10 mg lyophilized vials. Custom pack sizes available through private-label fulfillment.
What’s the standard purity?
99%+ verified by HPLC and confirmed by mass spectrometry. The full COA ships with every batch.
Are sample COAs available?
Yes. Verified partners can request COAs from recent batches before placing an order.
How is MOTS-c stored?
Lyophilized at −20°C for long-term stability. After reconstitution, store at 2–8°C and use within the documented stability window appropriate to the research application.
Get started
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These statements have not been evaluated by the FDA. Not intended to diagnose, treat, cure, or prevent any condition. For research purposes only — not for human consumption. PeptideDropship sells research-grade peptides exclusively to verified B2B partners under research-use-only labeling. MOTS-c is supplied for laboratory research applications only.